Table of Contents    
Case Report
 
Primary malignant lymphoma of testis in a young immune competent adult: A case report
Vandana Rana1, Devika Gupta1, Rajat Jagani1, Giriraj Singh2
1Associate Professor, Armed Forces Medical College, Department of Pathology and Laboratory Science, Command Hospital, Pune, India.
2Associate Professor, Armed Forces Medical College, Department of Radio diagnosis and Imaging, Command Hospital, Pune, India.

Article ID: 100001P03VR2014
doi:10.5348/P03-2014-1-CR-1

Address correspondence to:
Dr. Vandana Rana
Associate Professor, Armed Forces Medical College
Department of Pathology and Laboratory Science, Command Hospital
Pune
India 411040
Phone: 919823988983
Email: drvandanarana@gmail.com

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How to cite this article
Rana V, Gupta D, Jagani R, Singh G. Primary malignant lymphoma of testis in a young immune competent adult: A case report. Edorium J Pathol 2014;1:1–5.


Abstract
Introduction: Primary testicular lymphoma (PTL) is a disease of elderly and is very rarely seen in young adults. In the era of human immunodeficiency virus (HIV) pandemic, changing age spectrum has been reported but it is an uncommon malignancy in immune competent young adult. Chances of misdiagnosis or delayed diagnosis are there due to same age group of presentation as that of germ cell tumors.
Case Report: A 35-year-old immune competent male presented with left testicular swelling for five months duration, he was being treated as a case of epididymo-orchitis. On fine-needle aspiration cytology impression of seminoma was favored but it turned out to be non-Hodgkin's lymphoma (NHL) of testis on histopathology following orchidectomy. There was no evidence of generalized lymphadenopathy or involvement of any other organ. On immunohistochemistry (IHC) studies diagnosis of diffuse large B cell lymphoma (DLBCL), non germinal cell type was made.
Conclusion: Testicular lymphomas are rare and aggressive tumors and timely diagnosis in early stage helps the prognosis. Even though our patient was immune competent, in the era of human immunodeficiency virus (HIV) pandemic with changing age spectrum it is important to consider lymphomas in differential diagnosis of testicular tumors even in young patients.

Keywords: Diffuse large B cell lymphoma (DLBCL), Human immunodeficiency virus (HIV), Primary testicular lymphoma (PTL), Immunohistochemistry (IHC), Lymphoma, Seminoma, non-Hodgkin's lymphoma (NHL), Testis


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Author Contributions
Vandana Rana – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Devika Gupta – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Rajat Jagani – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Giriraj Singh – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2014 Vandana Rana et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.



About The Authors

Vandana Rana is Associate Professor in Department of Pathology, Command Hospital (SC), affiliated to Armed Forces Medical College, Pune, India. She has earned her MBBS and MD (Pathology) from PGIMS Rohtak, Haryana, India. She has been working in field of Oncopathology for last seven years. Her research interests include breast and lymphoid malignancies. She has active interest in teaching. She intends to keep on upgrading and expanding her horizons. Email: drvandanarana@gmail.com



Devika Gupta is Assistant Professor in department of Pathology, Command Hospital (SC), affiliated to Armed Forces Medical College, Pune, India. She has earned the undergraduate degree MBBS from Armed Forces Medical College (Pune University), India and postgraduate degree of MD Pathology and DNB Pathology from Delhi University, India. She has published 15 research papers in national and international academic Journals. Her research interests include haematolymphoid malignancies and blood coagulation disorders. She intends to pursue fellowship in transplant immunology in future.



Rajat Jagani is Associate Professor in Department of Pathology, Command Hospital (SC), affiliated to Armed Forces Medical College, Pune, India. He earned his undergraduate degree MBBS and postgraduate degree from University of Pune, Pune Maharashtra, India. He has done Long Term Training in Oncopathology at Post Graduate Institute of Medical Education and Research, Chandigarh India. He has published seven research papers in national and international academic journals. His research interests include prostate pathology, breast pathology and effusion cytology. He intends to pursue PhD in oncopathology in future.



Giriraj Singh is Professor at Department of Radio diagnosis, Command Hospital (Southern Command), affiliated to Armed Forces Medical College, Pune, India. He earned his MBBS degree from Armed Forces Medical College (Pune University), India and postgraduate degree of MD Radio diagnosis and DNB Radio diagnosis from Pune University, India. He has done Long-Term Training in cross-sectional imaging at All India Institute of Medical Sciences, New Delhi, India. He has published 13 research papers in national and international journals. His research interests include magnetic resonance cholangiopancreatography (MRCP) and pediatric oncoradiology. Email: girigujral@gmail.com